Here is the Ultimate HBCU Sports Division I Top 10 football poll after Week 6 of the regular season.
| Rank | Team | Previous rank | Record |
| 1 | Jackson State | 1 | 5-0 |
| 2 | Alcorn State | 3 | 3-2 |
| 3 | Florida A&M | 4 | 4-2 |
| 4 | North Carolina Central | 5 | 4-1 |
| 5 | Southern | NR | 3-2 |
| 6 | Delaware State | 8 | 3-2 |
| 7 | Prairie View | 2 | 3-3 |
| 8 | Alabama State | 6 | 3-3 |
| 9 | Hampton | 7 | 3-2 |
| 10 | North Carolina A&T | 10 | 2-3 |
