Here is the Ultimate HBCU Sports Division I Top 10 football poll after Week 2 of the regular season.
| Rank | Team | Previous rank | Record |
| 1 | Jackson State | 1 | 2-0 |
| 2 | North Carolina Central | 2 | 2-0 |
| 3 | Arkansas-Pine Bluff | 8 | 2-0 |
| 4 | Hampton | 9 | 2-0 |
| 5 | Grambling State | NR | 1-1 |
| 6 | Alabama State | 3 | 2-1 |
| 7 | South Carolina State | NR | 1-1 |
| 8 | Southern | 4 | 1-1 |
| 9 | Prairie View | 7 | 1-1 |
| 10 | Florida A&M | NR | 1-2 |
